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Vaccine. 1992;10(11):740-1.

Recombinant versus plasma-derived hepatitis B vaccine: comparison of immunogenicity in medical students.

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  • 1Institut für Hygiene, Leopold-Franzens-Universität, Innsbruck, Austria.

Abstract

A group of 92 medical students were immunized with a commercial recombinant hepatitis B vaccine (Engerix B). Antibody responses were determined and compared with those to plasma-derived Pasteur vaccine, obtained in 1986. Antibody concentrations were significantly higher in the group given recombinant vaccine, therefore this vaccine has superior immunogenicity and probably confers extended duration of protection.

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PMID:
1308114
[PubMed - indexed for MEDLINE]
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