J Exp Med. 1952 May;96(4):389-400.

Studies on the propagation in vitro of poliomyelitis viruses. III. The propagation of poliomyelitis viruses in tissue cultures devoid of nerve cells.

Abstract

Cells like fibroblasts, having no resemblance whatever to nerve cells were obtained in morphologically pure cultures from monkey testicular tissue and were found to support the growth in vitro of poliomyelitis virus, Type 2, Yale-SK strain. Moreover, these cells were destroyed as a result of the multiplication of this virus within them. Similarly, "fibroblasts" propagated in primary explant cultures of testicle were destroyed by poliomyelitis viruses, Types 1 and 2. Type specific antibodies neutralized the pathogenic effect of poliomyelitis virus on monkey testicular fibroblasts.

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Studies on the propagation in vitro of poliomyelitis viruses. I. Viral multiplications in tissue cultures employing monkey and human testicular cells. [J Exp Med. 1952]
Studies on the propagation in vitro of poliomyelitis viruses. I. Viral multiplications in tissue cultures employing monkey and human testicular cells.
SYVERTON JT, SCHERER WF. J Exp Med. 1952 May; 96(4):355-67.
Studies on the propagation in vitro of poliomyelitis viruses. II. A description of the growth curve and its relation to the cytopathogenicity of poliomyelitis virus. [J Exp Med. 1952]
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Poliomyelitis viruses in tissue culture. III. Susceptibility of testicular tissue from immune monkeys. [Proc Soc Exp Biol Med. 1952]
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Cited by 5 PubMed Central articles

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Studies on the propagation in vitro of poliomyelitis viruses. III. The propaga...
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Studies on the propagation in vitro of poliomyelitis viruses. III. The propagation of poliomyelitis viruses in tissue cultures devoid of nerve cells.

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