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J Pediatr. 2003 Aug;143(2):258-63.

Left ventricular outflow obstruction in rhabdomyoma of infancy: meta-analysis of the literature.

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  • 1Departments of Pediatrics and Cardiac Surgery, University and University Hospital of Ghent, De Pintelaan 185, B-9000 Ghent, Belgium.


Primary heart tumors are exceptional in infants and children. Most common is the rhabdomyoma, often associated with tuberous sclerosis (Bourneville's disease). This tumor is generally believed to have no hemodynamic effects in the majority of cases. Recently, severe obstruction of the left ventricular outflow tract by a solitary tumor was diagnosed during pregnancy and emergency surgery was needed soon after birth.

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