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Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305-5126, USA. peropa@leland.stanford.edu
The immunogenetics of cell-surface antigens began with the study of red cells and then moved onto the white cells. HLA class I antigens were analyzed on leukocytes and HLA class II antigens on B cells. In the last decade the natural killer (NK) cell has become a target for immunogeneticists, in particular the family of genes encoding the killer-cell immunoglobulin-like receptors (KIRs).
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