J Biotechnol. 2003 Sep 4;104(1-3):273-85.

Genome-wide expression analysis in Corynebacterium glutamicum using DNA microarrays.

Source

Institute of Biotechnology, 1 Research Center Jülich, D-52428 Jülich, Germany. v.wendisch@fz-juelich.de

Abstract

DNA microarray technology has become an important research tool for microbiology and biotechnology as it allows for comprehensive DNA and RNA analyses to characterize genetic diversity and gene expression in a genome-wide manner. DNA microarrays have been applied extensively to study the biology of many bacteria including Mycobacterium tuberculosis, but only recently have they been used for the related high-GC Gram-positive Corynebacterium glutamicum, which is widely used for biotechnological amino acid production. Besides the design and generation of microarrays as well as their use in hybridization experiments and subsequent data analysis, recent applications of DNA microarray technology in C. glutamicum including the characterization of ribose-specific gene expression and the valine stress response will be described. Emerging perspectives of functional genomics to enlarge our insight into fundamental biology of C. glutamicum and their impact on applied biotechnology will be discussed.

PMID:: 12948645; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Proteome

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Supplemental Content

Save items

Related citations in PubMed

Review Genomewide expression analysis in amino acid-producing bacteria using DNA microarrays. [Appl Biochem Biotechnol. 2004]
Review Genomewide expression analysis in amino acid-producing bacteria using DNA microarrays.
Polen T, Wendisch VF. Appl Biochem Biotechnol. 2004 Jul-Sep; 118(1-3):215-32.
Review Emerging Corynebacterium glutamicum systems biology. [J Biotechnol. 2006]
Review Emerging Corynebacterium glutamicum systems biology.
Wendisch VF, Bott M, Kalinowski J, Oldiges M, Wiechert W. J Biotechnol. 2006 Jun 25; 124(1):74-92. Epub 2006 Jan 10.
Review The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. [J Biotechnol. 2003]
Review The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.
Kalinowski J, Bathe B, Bartels D, Bischoff N, Bott M, Burkovski A, Dusch N, Eggeling L, Eikmanns BJ, Gaigalat L, et al. J Biotechnol. 2003 Sep 4; 104(1-3):5-25.
Development of a Corynebacterium glutamicum DNA microarray and validation by genome-wide expression profiling during growth with propionate as carbon source. [J Biotechnol. 2003]
Development of a Corynebacterium glutamicum DNA microarray and validation by genome-wide expression profiling during growth with propionate as carbon source.
Hüser AT, Becker A, Brune I, Dondrup M, Kalinowski J, Plassmeier J, Pühler A, Wiegräbe I, Tauch A. J Biotechnol. 2003 Dec 19; 106(2-3):269-86.
Review Genome-wide transcription profiling of Corynebacterium glutamicum after heat shock and during growth on acetate and glucose. [J Biotechnol. 2002]
Review Genome-wide transcription profiling of Corynebacterium glutamicum after heat shock and during growth on acetate and glucose.
Muffler A, Bettermann S, Haushalter M, Hörlein A, Neveling U, Schramm M, Sorgenfrei O. J Biotechnol. 2002 Sep 25; 98(2-3):255-68.

See reviews... See all...

Cited by 15 PubMed Central articles

Phosphotransferase system-independent glucose utilization in corynebacterium glutamicum by inositol permeases and glucokinases. [Appl Environ Microbiol. 2011]
Phosphotransferase system-independent glucose utilization in corynebacterium glutamicum by inositol permeases and glucokinases.
Lindner SN, Seibold GM, Henrich A, Krämer R, Wendisch VF. Appl Environ Microbiol. 2011 Jun; 77(11):3571-81. Epub 2011 Apr 8.
Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate. [BMC Microbiol. 2010]
Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate.
Kato O, Youn JW, Stansen KC, Matsui D, Oikawa T, Wendisch VF. BMC Microbiol. 2010 Dec 15; 10:321. Epub 2010 Dec 15.
Characterization of the dicarboxylate transporter DctA in Corynebacterium glutamicum. [J Bacteriol. 2009]
Characterization of the dicarboxylate transporter DctA in Corynebacterium glutamicum.
Youn JW, Jolkver E, Krämer R, Marin K, Wendisch VF. J Bacteriol. 2009 Sep; 191(17):5480-8. Epub 2009 Jul 6.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Genome-wide expression analysis in Corynebacterium glutamicum using DNA microarr...
Genome-wide expression analysis in Corynebacterium glutamicum using DNA microarrays.
J Biotechnol. 2003 Sep 4 ;104(1-3):273-85.

PubMed
Shi-quan-da-bu-tang (ten significant tonic decoction), SQT. A potent Chinese bio...
Shi-quan-da-bu-tang (ten significant tonic decoction), SQT. A potent Chinese biological response modifier in cancer immunotherapy, potentiation and detoxification of anticancer drugs.
Methods Find Exp Clin Pharmacol. 1992 Nov ;14(9):725-36.

PubMed
The effects of V2 antagonist (OPC-31260) on endolymphatic hydrops.
The effects of V2 antagonist (OPC-31260) on endolymphatic hydrops.
Hear Res. 2003 Aug ;182(1-2):9-18.

PubMed
A school outbreak of Norwalk-like virus: evidence for airborne transmission.
A school outbreak of Norwalk-like virus: evidence for airborne transmission.
Epidemiol Infect. 2003 Aug ;131(1):727-36.

PubMed
Ex vivo expansion of corneal limbal epithelial/stem cells for corneal surface re...
Ex vivo expansion of corneal limbal epithelial/stem cells for corneal surface reconstruction.
Eur J Ophthalmol. 2003 Jul ;13(6):515-24.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: