1-[2-(4-nitrophenoxy)acetyl]pyrrolidin-2-one: an antiamnesic agent

Acta Crystallogr C. 2003 Sep;59(Pt 9):o514-5. doi: 10.1107/s0108270103014823. Epub 2003 Aug 9.

Abstract

The title compound, C(12)H(12)N(2)O(5), is a potential antiamnesic agent. The pyrrolidinone ring has an envelope conformation, and the central moiety is almost coplanar with the planes of the phenyl and pyrrolidinone rings. In the crystal structure, weak intermolecular C--H...O interactions link the molecules into a complex network that can be described by R(2)(2)(X) rings (X = 16, 20 and 26) and a C(12) chain.

MeSH terms

  • Amnesia / drug therapy
  • Crystallography, X-Ray
  • Hydrogen Bonding
  • Molecular Conformation
  • Molecular Structure
  • Nootropic Agents / chemistry*
  • Nootropic Agents / pharmacology
  • Pyrrolidinones / chemistry*
  • Pyrrolidinones / pharmacology

Substances

  • 1-(2-(4-nitrophenoxy)acetyl)pyrrolidin-2-one
  • Nootropic Agents
  • Pyrrolidinones