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    Neurology. 2003 Aug 26;61(4):551-4.

    Interrupted therapy: stopping and switching of the beta-interferons prescribed for MS.

    Tremlett HL, Oger J.

    Source

    Division of Neurology, Department of Medicine, University of British Columbia, Vancouver Hospital and Health Sciences Center, Canada. tremlett@interchange.ubc.ca

    Abstract

    A retrospective chart review of patients in British Columbia with multiple sclerosis prescribed beta-interferon (IFNbeta) between 1995 and 2001 was carried out to investigate reasons for the interruption of therapy. The highest proportion of interruptions (76/281; 27%) occurred in the first 6 months. The single most common reason was perceived lack of efficacy, cited by 84 of 281 (30%). Gender, disability, and disease duration were identified as factors influencing interruption of IFNbeta therapy.

    PMID:
    12939437
    [PubMed - indexed for MEDLINE]

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