[Differences in the responses of taste receptors to organic and inorganic acids with changes in the concentration of bicarbonate in the solution]

Fiziol Zh SSSR Im I M Sechenova. 1975 Jun;61(7):1000-7.
[Article in Russian]

Abstract

The thresholds of the pH for citric acid (pH=4.9) were found to exceed by 1.4 pH the thresholds for HC1 (3.5) at 1.2 mmol/1 bicarbonate in the solution. The reaction to citric acid was higher than to HC1 at equal pH. Decreasing of bicarbonate from 1.2 mmol/1 to 0 reduced pH threshold only for sitric acid from 4.90 to 3.15. pH threshold for HC1 remained 3.5 The chorda tympani response to stimulation with solutions containing bicarbonate (1.2 mmol/1) was higher than in absence of bicarbonate. The data obtained suggest two ranges of the acids in action.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Bicarbonates / pharmacology
  • Cats
  • Chorda Tympani Nerve / physiology*
  • Citrates / pharmacology*
  • Dose-Response Relationship, Drug
  • Electrophysiology
  • Hydrochloric Acid / pharmacology*
  • Hydrogen-Ion Concentration
  • Taste Buds / drug effects*

Substances

  • Bicarbonates
  • Citrates
  • Hydrochloric Acid