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J Matern Fetal Neonatal Med. 2003 May;13(5):292-9.

Fetal programming for adult disease: where next?

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  • 1Maternal and Fetal Research Unit, St. Thomas' Hospital, London, UK.

Abstract

The Barker hypothesis of fetal programming for adult cardiovascular and metabolic diseases has attracted much interest over the past few years. In this review, we summarize the main studies in this field, give a brief outline of some of the laboratory models used to investigate this hypothesis and discuss potential mechanisms underlying these clinical observations that are amenable to future research.

[PubMed - indexed for MEDLINE]
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