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Insect Biochem Mol Biol. 2003 Sep;33(9):865-82.

A catalogue of Anopheles gambiae transcripts significantly more or less expressed following a blood meal.

Author information

  • National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-0425, USA. jribeiro@nih.gov


The recent assembly of the Anopheles gambiae genome included the sequencing of ~80,000 EST from blood fed (BF) and non-blood fed (NBF) adult female mosquitoes to help find the exons and introns in the mosquito genome. These two EST libraries provided an insight into the differential gene expression resulting from the metabolically intense task of converting the massive blood meal into eggs. Previously, 168 genes have been identified to be either significantly more or significantly less transcribed after the blood meal [Science 298 (2002) 129]. Presently, 435 transcripts are described; these are grouped in supplemental tables by probable function to facilitate public access to these data and to help in designing postgenome experiments in the biology of Anopheles gambiae. The electronic tables and supplemental material are available at http://www.ncbi.nlm.nih.gov/projects/Mosquito/Ag-ESTs.

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