IL-5 expression in the sputum of patients with bronchial asthma

A E Sazonov; F I Petrovskii; I I Ivanchuk; E A Gereng; L M Ogorodova

doi:10.1023/a:1024669016359

IL-5 expression in the sputum of patients with bronchial asthma

Bull Exp Biol Med. 2003 Apr;135(4):374-6. doi: 10.1023/a:1024669016359.

Authors

A E Sazonov¹, F I Petrovskii, I I Ivanchuk, E A Gereng, L M Ogorodova

Affiliation

¹ Siberian State Medical University, Tomsk.

PMID: 12910312
DOI: 10.1023/a:1024669016359

Abstract

Expression of IL-5 mRNA and the content of IL-5 in the sputum of patients with asthma of different severity were studied before and after treatment. The expression of IL-5 mRNA in mild asthma differed from that in severe and moderate asthma before and after treatment. The level of IL-5 before therapy was different in patients with mild and severe disease. In patients with severe asthma the level of IL-5 differed before and after treatment.

MeSH terms

Adrenal Cortex Hormones / administration & dosage
Adrenal Cortex Hormones / therapeutic use
Adult
Asthma / drug therapy
Asthma / immunology*
Asthma / metabolism
Asthma / pathology
Humans
Interleukin-5 / genetics
Interleukin-5 / metabolism*
Peak Expiratory Flow Rate
RNA, Messenger / analysis
Sputum / chemistry*

Substances

Adrenal Cortex Hormones
Interleukin-5
RNA, Messenger