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Curr Biol. 2003 Aug 5;13(15):R589-91.

Cytokinesis: a logical GAP.

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  • 1Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, A-1030, Vienna, Austria.

Abstract

Two complexes localize to the central spindle and regulate completion of cytokinesis: one, centralspindlin, contains a kinesin-like protein and a Rho-family GAP; the second contains Aurora B kinase. Aurora B kinase is known to regulate localization of centralspindlin and may regulate the activity of the RhoGAP component of centralspindlin.

PMID:
12906808
[PubMed - indexed for MEDLINE]
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