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    J Clin Microbiol. 2003 Aug;41(8):3873-6.

    Identification of the hypervirulent lineages of Neisseria meningitidis, the ST-8 and ST-11 complexes, by using monoclonal antibodies specific to NmeDI.

    Source

    Institute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.

    Abstract

    Most cases of serogroup C meningococcal disease are caused by the clonal lineages ST-8 and ST-11. The gene encoding the putative restriction-modification system NmeDI is specific to these lineages. We report here a monoclonal antibody directed against the NmeDI endonuclease as a tool for their rapid and spe-cific identification.

    PMID:
    12904407
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC179822
    Free PMC Article

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