Display Settings:

Format

Send to:

Choose Destination
Physiol Res. 2003;52(4):461-6.

Hepatoprotective effect of rooibos tea (Aspalathus linearis) on CCl4-induced liver damage in rats.

Author information

  • 1Institute of Animal Biochemistry and Genetics, Slovak Academy of Sciences, Moyzesova Str. 61, 900 28 Ivanka pri Dunaji. Slovak Republic. Miloslav.Greksak@savba.sk

Abstract

Hepatoprotective properties of rooibos tea (Aspalathus linearis) were investigated in a rat model of liver injury induced by carbon tetrachloride (CCl(4)). Rooibos tea, like N-acetyl-L-cysteine which was used for the comparison, showed histological regression of steatosis and cirrhosis in the liver tissue with a significant inhibition of the increase of liver tissue concentrations of malondialdehyde, triacylglycerols and cholesterol. Simultaneously, rooibos tea significantly suppressed mainly the increase in plasma activities of aminotransferases (ALT, AST), alkaline phosphatase and billirubin concentrations, which are considered as markers of liver functional state. The antifibrotic effect in the experimental model of hepatic cirrhosis of rats suggests the use of rooibos tea as a plant hepatoprotector in the diet of patients with hepatopathies.

PMID:
12899659
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Institute of Physiology, Academy of Sciences of the Czech Republic, Prague
    Loading ...
    Write to the Help Desk