J Investig Dermatol Symp Proc. 2003 Jun;8(1):20-3.

Use of finasteride in the treatment of men with androgenetic alopecia (male pattern hair loss).

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Division of Dermatology, University of British Columbia, Vancouver General Hospital, Vancouver, British Columbia, Canada.

Abstract

Finasteride, a type 2-selective 5alpha-reductase inhibitor, was approved in 1997 as the first oral pharmacologic therapy for the treatment of men with androgenetic alopecia (AGA; male pattern hair loss). Originally developed for the treatment of men with benign prostatic hyperplasia (BPH) at a dose of 5 mg/day, finasteride has a well-established, excellent safety profile. Subsequent studies demonstrated that finasteride was an effective treatment for men with AGA at an optimal dose of 1 mg/day. This report summarizes the published peer-reviewed literature on the use of finasteride in the treatment of men with AGA, including the data on long-term (5 years) use of finasteride in a placebo-controlled clinical trial environment.

PMID:: 12894990; [PubMed - indexed for MEDLINE]

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Review Finasteride in the treatment of alopecia. [Expert Opin Pharmacother. 2004]
Review Finasteride in the treatment of alopecia.
Libecco JF, Bergfeld WF. Expert Opin Pharmacother. 2004 Apr; 5(4):933-40.
Review Advances in the treatment of male androgenetic alopecia: a brief review of finasteride studies. [Eur J Dermatol. 2001]
Review Advances in the treatment of male androgenetic alopecia: a brief review of finasteride studies.
Whiting DA. Eur J Dermatol. 2001 Jul-Aug; 11(4):332-4.
Finasteride, a Type 2 5alpha-reductase inhibitor, in the treatment of men with androgenetic alopecia. [Expert Opin Investig Drugs. 1999]
Finasteride, a Type 2 5alpha-reductase inhibitor, in the treatment of men with androgenetic alopecia.
Kaufman KD, Dawber RP. Expert Opin Investig Drugs. 1999 Apr; 8(4):403-15.
Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group. [J Am Acad Dermatol. 1998]
Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group.
Kaufman KD, Olsen EA, Whiting D, Savin R, DeVillez R, Bergfeld W, Price VH, Van Neste D, Roberts JL, Hordinsky M, et al. J Am Acad Dermatol. 1998 Oct; 39(4 Pt 1):578-89.
Finasteride: a review of its use in male pattern hair loss. [Drugs. 1999]
Finasteride: a review of its use in male pattern hair loss.
McClellan KJ, Markham A. Drugs. 1999 Jan; 57(1):111-26.

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