Studying the interaction of alpha-gal carbohydrate antigen and proteins by quartz-crystal microbalance

J Am Chem Soc. 2003 Aug 6;125(31):9292-3. doi: 10.1021/ja035350a.

Abstract

The interaction of alpha-galacosyl antigen and its binding protein (anti-Gal antibody) has been studied by quartz crystal microbalance through a SAM immobilization technique which overcomes the nonspecific interactions and molecule trapping for current piezoelectric biosensors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antigens / chemistry*
  • Antigens / immunology
  • Biofilms
  • Concanavalin A / chemistry*
  • Concanavalin A / immunology
  • Galactose / chemistry*
  • Galactose / immunology
  • Gold / chemistry
  • Kinetics
  • Quartz / chemistry

Substances

  • Antigens
  • Concanavalin A
  • Quartz
  • Gold
  • Galactose