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Exerc Sport Sci Rev. 2003 Jul;31(3):111-6.

Translational control mechanisms modulate skeletal muscle gene expression during hypertrophy.

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  • 1Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, 17033, USA.


Understanding the basic mechanisms regulating skeletal muscle hypertrophy is essential to providing strategies for optimizing and maintaining skeletal muscle mass. This review focuses on the importance of mRNA translation in mediating acute increases in protein synthesis after resistance exercise as well as the anabolic response of muscle growth.

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