Scand J Infect Dis. 1992;24(6):815-7.

Isolated severe thrombocytopenia and bleeding caused by piperacillin.

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Department of Internal Medicine, St. Elizabeth Hospital Medical Center, Youngstown, Ohio 44501-1790.

Abstract

Bleeding and severe thrombocytopenia developed in a 71-year-old man who had been receiving piperacillin 5 g intravenously every 8 h for 9 days for the treatment of Pseudomonas aeruginosa septicemia. After piperacillin was discontinued, the platelet counts became normal. Rechallenge was made with 2 g of piperacillin intravenously resulting in thrombocytopenia within 6 h of piperacillin administration. The platelet count normalized after 3 days when no further piperacillin was given.

PMID:: 1287819; [PubMed - indexed for MEDLINE]

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Piperacillin

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