Your browser version may not work well with NCBI's Web applications. More information here...
1: Implant Dent. 2003;12(2):170-4. Links

Clinical, radiographic, histologic, and histomorphometric comparison of PepGen P-15 particulate and PepGen P-15 flow in extraction sockets: a same-mouth case study.

Hahn J, Rohrer MD, Tofe AJ.

Division of Oral & Maxillofacial Pathology, University of Minnesota School of Dentistry, Minneapolis, Minnesota, USA. cid@iglou.com

PURPOSE: Although the efficacy of PepGen P-15 particulate has been conclusively demonstrated in two multicenter clinical studies, the effect of a new hydrogel formulation containing PepGen P-15 on bone repair has not been previously demonstrated. MATERIALS AND METHODS: PepGen P-15 Flow contains PepGen P-15 particulate in a biocompatible hydrogel, which provides spacing between the particles. In this case study, bone repair of both PepGen P-15 particles and PepGen P-15 Flow was compared to natural bone in same-mouth extraction sockets. RESULTS: The radiographic, histologic, and histomorphometric evaluations showed enhanced bone formation and faster particle resorption with PepGen P-15 Flow compared to the PepGen P-15 particulate. CONCLUSION: The accelerated bone formation by PepGen P-15 Flow may provide faster implant placement.

PMID: 12861886 [PubMed - indexed for MEDLINE]