A chemical approach to generate molecular diversit...[J Comb Chem. 2003 Jul-Aug]

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1: J Comb Chem. 2003 Jul-Aug;5(4):353-5. Links

A chemical approach to generate molecular diversity based on the scaffold of cyclic decapeptide antibiotic tyrocidine A.

Qin C, Bu X, Wu X, Guo Z.

Department of Chemistry and Biotechnology Research Institute, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China.

PMID: 12857101 [PubMed - indexed for MEDLINE]

Dissociation of antibacterial and hemolytic activities of an amphipathic peptide antibiotic.
J Med Chem. 2003 Nov 6; 46(23):4830-3.

[J Med Chem. 2003]
Synthesis of tyrocidine A and its analogues by spontaneous cyclization in aqueous solution.
Org Lett. 2002 Aug 22; 4(17):2893-5.

[Org Lett. 2002]
High-throughput sequence determination of cyclic peptide library members by partial Edman degradation/mass spectrometry.
J Am Chem Soc. 2006 Oct 4; 128(39):13000-9.

[J Am Chem Soc. 2006]
ReviewChemistry and biology of cyclic depsipeptides of medicinal and biological interest.
Curr Med Chem. 2004 May; 11(10):1309-32.

[Curr Med Chem. 2004]
ReviewExploring privileged structures: the combinatorial synthesis of cyclic peptides.
Mol Divers. 2002; 5(4):289-304.

[Mol Divers. 2002]
» See reviews... | » See all...

Cited by 1 PubMed Central article

Development of Tyrocidine A analogues with improved antibacterial activity.
Marques MA, Citron DM, Wang CC. Bioorg Med Chem. 2007 Nov 1; 15(21):6667-77. Epub 2007 Aug 11.

[Bioorg Med Chem. 2007]

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