J Palliat Med. 2003 Apr;6(2):251-5.

Olanzapine for intractable nausea in palliative care patients.

Source

Department of Family Medicine, The University of Tennessee Health Sciences Center, Memphis, Tennessee 38104, USA. wcjackson@utmen.edu

Abstract

Nausea is a common problem among palliative care patients, which is often undertreated. Olanzapine, an atypical antipsychotic, possesses a unique neurotransmitter binding profile that is similar to methotrimeprazine, an anti-emetic widely used in Europe for recalcitrant nausea. We report a case series of six patients who suffered nausea which was resistant to initial treatment with traditional antiemetics; each patient exhibited marked improvement when treated with olanzapine.

PMID:: 12854942; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Case Reports

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Supplemental Content

Save items

Related citations in PubMed

Olanzapine as an antiemetic in refractory nausea and vomiting in advanced cancer. [J Pain Symptom Manage. 2003]
Olanzapine as an antiemetic in refractory nausea and vomiting in advanced cancer.
Srivastava M, Brito-Dellan N, Davis MP, Leach M, Lagman R. J Pain Symptom Manage. 2003 Jun; 25(6):578-82.
A pilot exploration of the antiemetic activity of olanzapine for the relief of nausea in patients with advanced cancer and pain. [J Pain Symptom Manage. 2002]
A pilot exploration of the antiemetic activity of olanzapine for the relief of nausea in patients with advanced cancer and pain.
Passik SD, Lundberg J, Kirsh KL, Theobald D, Donaghy K, Holtsclaw E, Cooper M, Dugan W. J Pain Symptom Manage. 2002 Jun; 23(6):526-32.
Re: Olanzapine-induced delirium. [J Pain Symptom Manage. 2005]
Re: Olanzapine-induced delirium.
Prommer E. J Pain Symptom Manage. 2005 Feb; 29(2):119-20.
Review Systematic review of the efficacy of antiemetics in the treatment of nausea in patients with far-advanced cancer. [Support Care Cancer. 2004]
Review Systematic review of the efficacy of antiemetics in the treatment of nausea in patients with far-advanced cancer.
Glare P, Pereira G, Kristjanson LJ, Stockler M, Tattersall M. Support Care Cancer. 2004 Jun; 12(6):432-40. Epub 2004 Apr 24.
Review [Cost-effectiveness analysis of schizophrenic patient care settings: impact of an atypical antipsychotic under long-acting injection formulation]. [Encephale. 2005]
Review [Cost-effectiveness analysis of schizophrenic patient care settings: impact of an atypical antipsychotic under long-acting injection formulation].
Llorca PM, Miadi-Fargier H, Lançon C, Jasso Mosqueda G, Casadebaig F, Philippe A, Guillon P, Mehnert A, Omnès LF, Chicoye A, et al. Encephale. 2005 Mar-Apr; 31(2):235-46.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Olanzapine for intractable nausea in palliative care patients.
Olanzapine for intractable nausea in palliative care patients.
J Palliat Med. 2003 Apr ;6(2):251-5.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: