Leuk Lymphoma. 2003 Jun;44(6):923-8.

Cord blood dendritic cells: subsets, functional characteristics and in vitro generation.

Source

Department of Histocompatibility and Immunogenetics, National Blood Service, Colindale Avenue, London NW9 5BG, UK. cristina.navarrete@nbs.nhs.uk

Abstract

Dendritic cells (DCs) form a heterogeneous population of cells capable of stimulating naive T cells and initiating primary immune responses. This well-known function of DCs has offered the possibility of developing clinical protocols for their use in immunotherapy to tumours. DCs may also play a critical role in the induction of peripheral immunological tolerance, which could have important implications in the treatment of autoimmunity or in the outcome of clinical transplantation. Recent reports have indicated that cord blood transplantation is associated with a reduced incidence of graft versus host disease. Thus studies on the identification and characterisation of DCs present in, or derived from cord blood will help to understand their role, not only in neonatal immunity, but also in the outcome of cord blood transplantation.

PMID:: 12854889; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Supplemental Content

Save items

Related citations in PubMed

Cord blood dendritic cells prevent the differentiation of naïve T-helper cells towards Th1 irrespective of their subtype. [Clin Exp Med. 2009]
Cord blood dendritic cells prevent the differentiation of naïve T-helper cells towards Th1 irrespective of their subtype.
Naderi N, Pourfathollah AA, Alimoghaddam K, Moazzeni SM. Clin Exp Med. 2009 Mar; 9(1):29-36. Epub 2008 Nov 1.
Generation of dendritic cells from fresh and frozen cord blood CD34+ cells. [Cryobiology. 1998]
Generation of dendritic cells from fresh and frozen cord blood CD34+ cells.
Sato K, Nagayama H, Takahashi TA. Cryobiology. 1998 Dec; 37(4):362-71.
Efficient lentiviral transduction of human cord blood CD34(+) cells followed by their expansion and differentiation into dendritic cells. [Exp Hematol. 2001]
Efficient lentiviral transduction of human cord blood CD34(+) cells followed by their expansion and differentiation into dendritic cells.
Oki M, Ando K, Hagihara M, Miyatake H, Shimizu T, Miyoshi H, Nakamura Y, Matsuzawa H, Sato T, Ueda Y, et al. Exp Hematol. 2001 Oct; 29(10):1210-7.
Review Cytokines in the generation and maturation of dendritic cells: recent advances. [Eur Cytokine Netw. 2002]
Review Cytokines in the generation and maturation of dendritic cells: recent advances.
Zou GM, Tam YK. Eur Cytokine Netw. 2002 Apr-Jun; 13(2):186-99.
Review Induction of anergic and regulatory T cells by plasmacytoid dendritic cells and other dendritic cell subsets. [Hum Immunol. 2002]
Review Induction of anergic and regulatory T cells by plasmacytoid dendritic cells and other dendritic cell subsets.
Kuwana M. Hum Immunol. 2002 Dec; 63(12):1156-63.

See reviews... See all...

Recent activity

Clear Turn Off Turn On

Cord blood dendritic cells: subsets, functional characteristics and in vitro gen...
Cord blood dendritic cells: subsets, functional characteristics and in vitro generation.
Leuk Lymphoma. 2003 Jun ;44(6):923-8.

PubMed
[Experimental and clinical islets transplantation. Current status].
[Experimental and clinical islets transplantation. Current status].
Zentralbl Chir. 1992 ;117(12):670-6.

PubMed
Review of air pollution and health impacts in Malaysia.
Review of air pollution and health impacts in Malaysia.
Environ Res. 2003 Jun ;92(2):71-7.

PubMed
[Annual study of anesthesia-related mortality and morbidity in the year 2001 in ...
[Annual study of anesthesia-related mortality and morbidity in the year 2001 in Japan: the outlines--report of Japanese Society of Anesthesiologists Committee on Operating Room Safety].
Masui. 2003 Jun ;52(6):666-82.

PubMed
Fetuin--an old friend revisited.
Fetuin--an old friend revisited.
Bioessays. 1992 Nov ;14(11):749-55.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: