Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
World J Gastroenterol. 2003 Jul;9(7):1598-600.

Meta analysis of risk factors for colorectal cancer.

Author information

  • 1Department of Epidemiology, School of Medicine, Zhejiang University, Hangzhou 310031, Zhejiang Province, China. ck@zjuem.zju.edu.cn

Abstract

AIM:

To study the risk factors for colorectal cancer in China.

METHODS:

A meta-analysis of the risk factors of colorectal cancer was conducted for 14 case-control studies, and reviewed 14 reports within 13 years which included 5034 cases and 5205 controls. Dersimonian and Laird random effective models were used to process the results.

RESULTS:

Meta analysis of the 14 studies demonstrated that proper physical activities and dietary fibers were protective factors (pooled OR<0.8), while fecal mucohemorrhage, chronic diarrhea and polyposis were highly associated with colorectal cancer (all pooled OR>4). The stratified results showed that different OR values of some factors were due to geographic factors or different resources.

CONCLUSION:

Risks of colorectal cancer are significantly associated with the histories of intestinal diseases or relative symptoms, high lipid diet, emotional trauma and family history of cancers. The suitable physical activities and dietary fibers are protective factors.

PMID:
12854172
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Baishideng Publishing Group Inc.
    Loading ...
    Write to the Help Desk