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1: Brain Inj. 2003 Aug;17(8):643-51.Click here to read Links

Theoretical basis for brain plasticity after a TBI.

Bach-y-Rita P.

Department of Orthopedics, University of Wisconsin-Madison, Madison, WI 53706, USA. pbachyri@facstaff.wisc.edu

Evidence has been accumulating that the brain can reorganize extensively after damage and that reorganization can be obtained even many years after the trauma with appropriate late rehabilitation. An understanding of the brain plasticity mechanisms should lead to more effective rehabilitation and neuropharmacology. In this communication, several emerging concepts with supporting experimental evidence have been presented. These include non-synaptic diffusion neurotransmission, extracellular space volume fraction, neurotransmitters, regeneration and neurogenesis and multiplexing.

PMID: 12850949 [PubMed - indexed for MEDLINE]