Division of Bone and Mineral Diseases, Department of Internal Medicine, Barnes-Jewish Hospital, North Campus, 216 S, Kingshighway Blvd, St, Louis, MO 63110, USA.
Recent microarray studies of mouse and human osteoblast differentiation in vitro have identified novel transcription factors that may be important in the establishment and maintenance of differentiation. These findings help unravel the pattern of gene-expression changes that underly the complex process of bone formation.