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J Vasc Surg. 2003 Jul;38(1):72-7.

Effectiveness and cost of screening for abdominal aortic aneurysm: results of a population screening program.

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  • 1Department of Vascular Surgery, University of Birmingham, Birmingham, England, United Kingdom.

Abstract

OBJECTIVES:

We undertook this study to calculate the cost per life-year gained in the first round of a screening program for abdominal aortic aneurysm (AAA) and to estimate the costs in a subsequent round.

METHODS:

This was an intervention study, with follow-up for ruptured aneurysms. Men older than 50 years were screened for asymptomatic AAA. Outcome measures included cost per life-year saved and number of men needed to be screened to save one life.

RESULTS:

The incidence of ruptured AAA was 2.6 per 10,000 person- years in the screening group and 7.1 per 10,000 person-years in the control group. Screening is estimated to have prevented 10.8 ruptured AAA and 8 deaths per year, gaining 51 life-years per year for the study population, and to have reduced the incidence of ruptured AAA by 64% (95% CI, 42%-77%). Each life-year gained during the first screening round cost $1107. To save one life, 1000 men need to be screened and 5 elective operations performed. We predict that a second round of screening can be cost neutral.

CONCLUSIONS:

The cost-effectiveness of screening for AAA compares favorably with screening programs for other disorders in adults.

PMID:
12844092
[PubMed - indexed for MEDLINE]
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