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Nucleic Acids Res. 2003 Jul 1;31(13):3723-6.

AMIGene: Annotation of MIcrobial Genes.

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  • 1Génoscope/UMR-CNRS 8030, Atelier de Génomique Comparative, 2 rue Gaston Crémieux, F-91006 Evry, France.


AMIGene (Annotation of MIcrobial Genes) is an application for automatically identifying the most likely coding sequences (CDSs) in a large contig or a complete bacterial genome sequence. The first step in AMIGene is dedicated to the construction of Markov models that fit the input genomic data (i.e. the gene model), followed by the combination of well-known gene-finding methods and an heuristic approach for the selection of the most likely CDSs. The web interface allows the user to select one or several gene models applied to the analysis of the input sequence by the AMIGene program and to visualize the list of predicted CDSs graphically and in a downloadable text format. The AMIGene web site is accessible at the following address: (


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