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    Nucleic Acids Res. 2003 Jul 1;31(13):3586-8.

    YMF: A program for discovery of novel transcription factor binding sites by statistical overrepresentation.

    Source

    Center for Studies in Physics and Biology, Box 25, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

    Abstract

    A fundamental challenge facing biologists is to identify DNA binding sites for unknown regulatory factors, given a collection of genes believed to be coregulated. The program YMF identifies good candidates for such binding sites by searching for statistically overrepresented motifs. More specifically, YMF enumerates all motifs in the search space and is guaranteed to produce those motifs with greatest z-scores. This note describes the YMF web software, available at http://bio.cs.washington.edu/software.html.

    PMID:
    12824371
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC169024
    Free PMC Article

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