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Rheumatol Int. 2004 May;24(3):141-6. Epub 2003 Jun 19.

Ventricular function abnormalities in active rheumatoid arthritis: a Doppler echocardiographic study.

Author information

  • 1Department of Physical Medicine and Rehabilitation, Meram Medical School of Selcuk University, Meram-Konya, Turkey. Levendogluf@hotmail.com

Abstract

OBJECTIVE:

The aim of the present study was to evaluate cardiac involvement in patients with active rheumatoid arthritis (RA).

METHODS:

Forty patients with active RA participated. All were submitted to standard Doppler echocardiography and myocardial performance index (MPI) grading.

RESULTS:

There were left and right ventricular diastolic function abnormalities in RA patients. Left ventricular MPI was also significantly higher than in controls ( P<0.05). A relationship was found between left ventricular early diastolic (E)/atrial (A) flow velocities (E/A ratio), isovolumic relaxation time (IRT), and disease duration ( r=-0.47 and P=0.002, r=0.618 and P=0.000, respectively).

CONCLUSION:

Diastolic function was impaired in both ventricles in patients with active RA. There was a direct relationship between some of the parameters of left ventricular diastolic function and disease duration as well. These findings suggest a subclinical myocardial involvement in RA patients.

PMID:
12819928
[PubMed - indexed for MEDLINE]
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