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Breast Cancer Res. 2003;5(4):192-7. Epub 2003 Apr 25.

Pregnancy-induced changes in cell-fate in the mammary gland.

Author information

  • 1Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA. mginger@bcm.tmc.edu

Abstract

The protective effect of an early full-term pregnancy is a well established phenomenon; in contrast, the molecular and cell-specific mechanisms that govern parity-specific changes in the mammary gland have not been well described. Recent studies signify a dramatic advance in our understanding of this phenomenon, and indicate a 'cell fate' model for parity-related changes that lead to protection against breast cancer.

PMID:
12817990
[PubMed - indexed for MEDLINE]
PMCID:
PMC165015
Free PMC Article

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