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J Clin Invest. 2003 Jun;111(12):1817-9.

An eye on insulin.

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  • 1Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania 17033, USA.

Abstract

Diabetic retinopathy, the most frequent complication of diabetes and leading cause of vision loss, involves vascular and neural damage in the retina. Insulin and IGF-1 signaling are now shown to contribute to retinal neovascularization, in part, by modulating the expression of various vascular mediators.

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PMID:
12813016
[PubMed - indexed for MEDLINE]
PMCID:
PMC161434
Free PMC Article

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