Rheum Dis Clin North Am. 1992 Nov;18(4):793-807.

T-cell receptor-major histocompatibility complex genetic interactions in rheumatoid arthritis.

Source

Cornell University Medical College, New York.

Abstract

Rheumatoid arthritis (RA) is a complex multifactorial illness. It is proposed that multiple genes involved in immune recognition interact to produce a state of genetic susceptibility for RA. The role of HLA and T-cell receptor and other background genes is discussed, with an emphasis on their role in shaping the T-cell repertoire.

PMID:: 1280847; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

LinkOut - more resources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Supplemental Content

Save items

Related citations in PubMed

Review Association of MHC and rheumatoid arthritis. HLA polymorphisms in phenotypic variants of rheumatoid arthritis. [Arthritis Res. 2000]
Review Association of MHC and rheumatoid arthritis. HLA polymorphisms in phenotypic variants of rheumatoid arthritis.
Weyand CM, Goronzy JJ. Arthritis Res. 2000; 2(3):212-6. Epub 2000 Apr 19.
HLA associations with rheumatoid arthritis: a piece of the puzzle. [J Rheumatol Suppl. 1992]
HLA associations with rheumatoid arthritis: a piece of the puzzle.
Gregersen PK. J Rheumatol Suppl. 1992 Jan; 32:7-11.
Use of T cell receptor/HLA-DRB1*04 molecular modeling to predict site-specific interactions for the DR shared epitope associated with rheumatoid arthritis. [Arthritis Rheum. 1997]
Use of T cell receptor/HLA-DRB1*04 molecular modeling to predict site-specific interactions for the DR shared epitope associated with rheumatoid arthritis.
Penzotti JE, Nepom GT, Lybrand TP. Arthritis Rheum. 1997 Jul; 40(7):1316-26.
Review Rheumatoid arthritis: a disease of chronic, low-amplitude signals transduced through T cell antigen receptors? [Wien Med Wochenschr. 2006]
Review Rheumatoid arthritis: a disease of chronic, low-amplitude signals transduced through T cell antigen receptors?
Zhang Z, Gorman C, Clark JM, Cope AP. Wien Med Wochenschr. 2006 Jan; 156(1-2):2-10.
Role of major histocompatibility complex genes in murine collagen-induced arthritis: a model for human rheumatoid arthritis. [Am J Med Sci. 2004]
Role of major histocompatibility complex genes in murine collagen-induced arthritis: a model for human rheumatoid arthritis.
David CS, Taneja V. Am J Med Sci. 2004 Apr; 327(4):180-7.

See reviews... See all...

Cited by 2 PubMed Central articles

ERK-dependent T cell receptor threshold calibration in rheumatoid arthritis. [J Immunol. 2009]
ERK-dependent T cell receptor threshold calibration in rheumatoid arthritis.
Singh K, Deshpande P, Pryshchep S, Colmegna I, Liarski V, Weyand CM, Goronzy JJ. J Immunol. 2009 Dec 15; 183(12):8258-67.
Role of enteric bacteria in the pathogenesis of rheumatoid arthritis: evidence for antibodies to enterobacterial common antigens in rheumatoid sera and synovial fluids. [Ann Rheum Dis. 1996]
Role of enteric bacteria in the pathogenesis of rheumatoid arthritis: evidence for antibodies to enterobacterial common antigens in rheumatoid sera and synovial fluids.
Aoki S, Yoshikawa K, Yokoyama T, Nonogaki T, Iwasaki S, Mitsui T, Niwa S. Ann Rheum Dis. 1996 Jun; 55(6):363-9.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

T-cell receptor-major histocompatibility complex genetic interactions in rheumat...
T-cell receptor-major histocompatibility complex genetic interactions in rheumatoid arthritis.
Rheum Dis Clin North Am. 1992 Nov ;18(4):793-807.

PubMed
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent...
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts.
Nature. 2003 Jul 3 ;424(6944):99-103. Epub 2003 May 28 .

PubMed
Identification of a high-risk haplotype for the dystrobrevin binding protein 1 (...
Identification of a high-risk haplotype for the dystrobrevin binding protein 1 (DTNBP1) gene in the Irish study of high-density schizophrenia families.
Mol Psychiatry. 2003 May ;8(5):499-510.

PubMed
Bizarre leiomyoma of the scrotum.
Bizarre leiomyoma of the scrotum.
J Korean Med Sci. 2003 Jun ;18(3):452-4.

PubMed
Intervention in Graves' disease. Choosing among imperfect but effective treatmen...
Intervention in Graves' disease. Choosing among imperfect but effective treatment options.
Postgrad Med. 1992 Dec ;92(8):117-24, 128-9, 133-4.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: