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Arq Neuropsiquiatr. 2003 Jun;61(2A):256-8. Epub 2003 Jun 9.

Botulinum toxin for treatment of Frey's syndrome: report of two cases.

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  • 1Movement Disorders Unit, Neurology Service, Hospital de ClĂ­nicas of Federal university of Paraná, Curitiba PR, Brazil. hagteive@mps.com.br


Frey's syndrome is a phenomenon of hemifacial flushing and sweating after gustatory stimulus, usually secondary to surgical trauma over the parotid gland, although other injury mechanisms may be seen. It is accepted as a result of aberrant regeneration of facial autonomic nerve fibers. Treatment evolved from ineffective medical and surgical approaches to botulinum toxin. We evaluate the effectiveness and safety of botulinum toxin in the treatment of this complication in two patients.

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