Trends Genet. 2003 Jun;19(6):345-51.

Phylogeny for the faint of heart: a tutorial.

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Department of Biology, University of York, Box 373, York, UK, YO10 5YW. slb14@york.ac.uk

Abstract

Phylogenetic trees seem to be finding ever broader applications, and researchers from very different backgrounds are becoming interested in what they might have to say. This tutorial aims to introduce the basics of building and interpreting phylogenetic trees. It is intended for those wanting to understand better what they are looking at when they look at someone else's trees or to begin learning how to build their own. Topics covered include: how to read a tree, assembling a dataset, multiple sequence alignment (how it works and when it does not), phylogenetic methods, bootstrap analysis and long-branch artefacts, and software and resources.

PMID:: 12801728; [PubMed - indexed for MEDLINE]

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