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Genome Biol. 2003;4(6):216. Epub 2003 May 29.

Matrix metalloproteinases: old dogs with new tricks.

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  • 1Department of Biomedical Engineering, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Abstract

The matrix metalloproteinase family in humans comprises 23 enzymes, which are involved in many biological processes and diseases. It was previously thought that these enzymes acted only to degrade components of the extracellular matrix, but this view has changed with the discovery that non-extracellular-matrix molecules are also substrates.

PMID:
12801404
[PubMed - indexed for MEDLINE]
PMCID:
PMC193609
Free PMC Article
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