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Department of Pediatrics, Division of Pediatric Hematology/Oncology/Blood and Marrow Transplantation, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA. tolar@lenti.med.umn.edu
Cancer in pregnancy is not rare, and the possibility of transmission of malignancy from mother to child, while infrequent, represents a clinical challenge for the primary pediatric hematologist-oncologist. The authors summarize all reported cases of vertically transmitted cancer and review other reported cases of person-to-person transfer of malignancy. As these cases represent a unique physiologic model of tumor transplantation, the biology of cancer transmission is discussed and provisional guidelines are given for the screening of infants born to women with cancer.
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