Aid to the antemortem diagnosis of Fell pony foal syndrome by the analysis of B lymphocytes

Vet Rec. 2003 May 17;152(20):618-21. doi: 10.1136/vr.152.20.618.

Abstract

Fell pony foals are affected by a congenital fatal immunodeficiency that commonly leads to anaemia and lymphopenia. Previous work has shown that the foals' circulating subpopulations of CD4 and CD8 T lymphocytes are unaffected. In this study it was shown that the mean population of B lymphocytes in 10 affected foals was less than 10 per cent of that in normal foals.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn
  • B-Lymphocytes / cytology*
  • B-Lymphocytes / immunology
  • Flow Cytometry
  • Horse Diseases / blood
  • Horse Diseases / diagnosis*
  • Horse Diseases / immunology
  • Horses
  • Immunologic Deficiency Syndromes / blood
  • Immunologic Deficiency Syndromes / diagnosis*
  • Immunologic Deficiency Syndromes / immunology
  • Immunologic Deficiency Syndromes / veterinary*
  • Lymphocyte Count
  • Syndrome