Gut. 1976 May;17(5):332-4.

Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis.

Simon M, Bourel M, Fauchet R, Genetet B.

Abstract

The frequency of HLA-A3 and HLA-B14 antigens was significantly higher in a series of 51 patients with idiopathic haemochromatosis than in a control group, being respectively 78-4 versus 27-0% and 25-5 versus 3-4%. This finding strongly supports the suggestion that idiopathic haemochromatosis is a genetic disease and suggests that the gene(s) responsible for the disease may be linked to the histocompatibility genes.

PMID:: 1278715; [PubMed - indexed for MEDLINE]
PMCID:: PMC1411133

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