Emerg Infect Dis. 2003 Jun;9(6):730-3.

Fluoroquinolone use and Clostridium difficile-associated diarrhea.

McCusker ME, Harris AD, Perencevich E, Roghmann MC.

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University of Maryland, Baltimore, Maryland, USA.

Abstract

We performed a case-control study to evaluate the association between antibiotic use and Clostridium difficile-associated diarrhea (CDAD), matching for admission unit and time at risk for CDAD. A multivariable regression model showed that treatment with fluoroquinolones (odds ratio 12.7; 95% confidence interval 2.6 to 61.6) was the strongest risk factor for CDAD.

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Emerg Infect Dis. 2003 Jun ;9(6):730-3.

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