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Neurology. 2004 Apr 27;62(8):1453.
Cardiac troponin levels following monitored epileptic seizures.
Woodruff BK,
Britton JW,
Tigaran S,
Cascino GD,
Burritt MF,
McConnell JP,
Ravkilde J,
Molgaard H,
Andreasen F,
Dam M,
Jaffe AS.
Department of Neurology, Mayo Clinic Rochester, MN 55905, USA.
Cardiac arrhythmia associated with myocardial injury is a proposed mechanism for sudden unexplained death in epilepsy. The authors measured serial cardiac troponin levels in 11 patients after monitored seizures. Using highly sensitive assays and criteria, no troponin elevations were seen, indicating that myocardial injury does not occur during uncomplicated seizures. An elevation in postictal troponin elevations should suggest the presence of cardiac injury secondary to neurocardiogenic mechanisms or primary cardiac factors, prompting further evaluation.
PMID: 12771269 [PubMed - indexed for MEDLINE]
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