Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Insect Physiol. 1999 Jan;45(1):39-44.

The formation of type-I concretions in Drosophila Malpighian tubules studied by electron microscopy and X-ray microanalysis.

Author information

  • 1Institut für Zoologie, Heinrich-Buff-Ring 29, 35392, Giessen, Germany

Abstract

There are two types of concretions in Drosophila Malpighian tubules: Type-I concretions originate in the distal segments of the anterior tubules, type-II concretions in the adjacent transitional segment between the apical microvilli. Type-I concretions are formed with the aid of carbonic anhydrase within intracellular vesicles, which migrate to the apical cell membrane where they are discharged into the lumen by exocytosis. The carbonic anhydrase inhibitors acetazolamide or hydrochlorothiazide prevent the formation of concretions by interruption of bicarbonate supply. In addition, the formation of concretions can be reduced by feeding with sodium cellulose phosphate.

PMID:
12770394
[PubMed - as supplied by publisher]

LinkOut - more resources

Full Text Sources

Molecular Biology Databases

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk