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Science. 2003 Jun 20;300(5627):1966-70. Epub 2003 May 23.

Transmission dynamics and control of severe acute respiratory syndrome.

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  • 1Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.

Abstract

Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemiologic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.

Comment in

PMID:
12766207
[PubMed - indexed for MEDLINE]
PMCID:
PMC2760158
Free PMC Article

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