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    Trends Plant Sci. 2003 May;8(5):195-7.

    Planning for remodelling: nuclear architecture, chromatin and chromosomes.

    Source

    Department of Biology, University of Leicester, Leicester LE1 7RH, UK. phh4@le.ac.uk

    Abstract

    DNA sequences occupy three-dimensional positions and their architecture is related to gene expression, gene-protein interactions and epigenetic processes. The recent analysis of chromosome 4 in Arabidopsis interphase nuclei reveals that gene-rich, undermethylated DNA is composed of active loops of 200 to 2000 kb associated with acetylated histones, providing a well-defined model system to study chromatin in its nuclear context.

    PMID:
    12758032
    [PubMed - indexed for MEDLINE]

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