Abstract
The effects of an oral preparation containing an extract of thyme and primula (Bronchipret; Bionorica) on the lung function of five horses suffering heaves were determined in a longitudinal study. The horses accepted the product well. The plasma concentrations of the marker substance, thymol, indicated that at least one of the substances in the extract had been absorbed from the gastrointestinal tract. The compliance, pulmonary pressure and airway resistance of the horses' lungs were all significantly improved after one month of treatment However, the severity of their clinical signs and their arterial oxygen partial pressure had not improved significantly.
Publication types
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Clinical Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Administration, Oral
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Airway Obstruction / drug therapy
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Airway Obstruction / veterinary*
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Animals
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Bronchodilator Agents / administration & dosage
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Bronchodilator Agents / therapeutic use*
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Horse Diseases / blood
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Horse Diseases / drug therapy*
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Horse Diseases / pathology
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Horses
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Longitudinal Studies
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Phytotherapy*
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Pilot Projects
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Plant Extracts / administration & dosage
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Plant Extracts / therapeutic use*
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Plant Roots
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Primula*
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Recurrence
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Respiratory Function Tests / veterinary
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Severity of Illness Index
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Thymol / administration & dosage
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Thymol / blood
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Thymol / therapeutic use*
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Thymus Plant*
Substances
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Bronchodilator Agents
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Plant Extracts
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thyme extract and ivy extract drug combination
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Thymol