Predominance of serotype V and frequency of erythromycin resistance in Streptococcus agalactiae in Ohio

Am J Obstet Gynecol. 2003 May;188(5):1148-50. doi: 10.1067/mob.2003.293.

Abstract

Objective: The purpose of this study was to test the serotype distribution and antibiotic sensitivity patterns of group B Streptococcus from three Ohio regions in comparison to other areas of the United States.

Study design: Three hundred forty-nine group B Streptococcus isolates from three Ohio hospitals were serotyped specifically, and disk diffusion was used to determine antibiotic susceptibility.

Results: Serotype V was isolated most frequently (27%); major types Ia, Ib, II, and III had frequencies of 18%, 9%, 11%, and 17%, respectively. Erythromycin and clindamycin resistance was 12% (n = 200 isolates) and 8% (n = 49 isolates), respectively.

Conclusion: The prevalence shift of resistant serotype V group B streptococci in Ohio reflects regional increases and suggests that alternative therapies for patients who are allergic to penicillin may be inadequate.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Clindamycin / pharmacology
  • Drug Resistance
  • Erythromycin / pharmacology*
  • Female
  • Humans
  • Ohio
  • Pregnancy
  • Serotyping
  • Streptococcus agalactiae / classification*
  • Streptococcus agalactiae / drug effects*
  • Streptococcus agalactiae / isolation & purification
  • Vagina / microbiology

Substances

  • Anti-Bacterial Agents
  • Clindamycin
  • Erythromycin