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    AJNR Am J Neuroradiol. 2003 May;24(5):952-5.

    Proton MR spectroscopy in Wernicke encephalopathy.

    Rugilo CA, Uribe Roca MC, Zurru MC, Capizzano AA, Pontello GA, Gatto EM.

    Servicio de Neurología, Buenos Aires, Argentina.

    Wernicke encephalopathy is caused by thiamine deficiency. Although the clinical picture has been well established for some time, clinical diagnosis is attained in only 20% of the cases. MR imaging techniques contribute to early diagnosis of Wernicke encephalopathy. We herein report MR imaging and proton MR spectroscopic findings for a patient with clinical and biochemical features consistent with Wernicke encephalopathy. Increased lactate and typical MR imaging findings are discussed in the context of the known pathophysiology of Wernicke encephalopathy.

    PMID: 12748100 [PubMed - indexed for MEDLINE]

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    Patient drug information

    • Thiamine

      Thiamine is a vitamin used by the body to break down sugars in the diet. The medication helps correct nerve and heart problems that occur when a person's diet does not contain enough thiamine.