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Curr Genet. 2003 Jul;43(4):225-44. Epub 2003 May 10.

Regulation of phosphate acquisition in Saccharomyces cerevisiae.

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  • 1Department of Chemistry and Biomedical Science, Kalmar University, P.O. Box 905, 39182, Kalmar, Sweden. Bengt.Persson@hik.se

Abstract

Membrane transport systems active in cellular inorganic phosphate (P(i)) acquisition play a key role in maintaining cellular P(i) homeostasis, independent of whether the cell is a unicellular microorganism or is contained in the tissue of a higher eukaryotic organism. Since unicellular eukaryotes such as yeast interact directly with the nutritious environment, regulation of P(i) transport is maintained solely by transduction of nutrient signals across the plasma membrane. The individual yeast cell thus recognizes nutrients that can act as both signals and sustenance. The present review provides an overview of P(i) acquisition via the plasma membrane P(i) transporters of Saccharomyces cerevisiae and the regulation of internal P(i) stores under the prevailing P(i) status.

PMID:
12740714
[PubMed - indexed for MEDLINE]
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