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Genome Biol. 2003;4(5):R35. Epub 2003 Apr 25.

GeneHopper: a web-based search engine to link gene-expression platforms through GenBank accession numbers.

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  • 1Center for Human and Clinical Genetics/Leiden Genome Technology Center, Leiden University Medical Center, The Netherlands.


Global gene-expression analysis is carried out using different technologies that are either array- or sequence-tag-based. To compare experiments that are performed on these different platforms, array probes and sequence tags need to be linked. An additional challenge is cross-referencing between species, to compare human profiles with those obtained in a mouse model, for example. We have developed the web-based search engine GeneHopper to link different expression resources based on UniGene clusters and HomoloGene orthologs databases of the National Center for Biotechnology Information (NCBI).

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