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Genome Biol. 2003;4(5):111. Epub 2003 Apr 29.

Genomic analysis of the eukaryotic protein kinase superfamily: a perspective.

Author information

  • Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. steve.hanks@vanderbilt.edu

Abstract

Protein kinases with a conserved catalytic domain make up one of the largest 'superfamilies' of eukaryotic proteins and play many key roles in biology and disease. Efforts to identify and classify all the members of the eukaryotic protein kinase superfamily have recently culminated in the mining of essentially complete human genome data.

PMID:
12734000
[PubMed - indexed for MEDLINE]
PMCID:
PMC156577
Free PMC Article

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