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J Perinatol. 2003 Apr-May;23(3):254-5.

Neonatal acute renal failure secondary to maternal exposure to telmisartan, angiotensin II receptor antagonist.

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  • 1Department of Pediatrics, American Memorial Hospital, Reims, France.


Fetal and neonatal toxic effects of angiotensin II receptor antagonists have been described in animals and humans. Five cases of fetal or neonatal deaths have been reported following maternal use of sartans for hypertension. We report a case of neonatal transient renal failure following telmisartan therapy during pregnancy. This class of antihypertensive drugs should be avoided during pregnancy and breastfeeding.

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